Senior Data Scientist - Process Modeling

fulltime
Expired

Employment Information

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About the Job


We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people's lives. We're also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?


The Senior Data Scientist- Process Modeling will be based in the Global CMC Development group in Research & Development (R&D) and will provide process modelling and data analytics support for cell line selection, cell culture process development, process scale-up and technology transfer for a wide range of biopharmaceuticals (mammalian, microbial and gene therapy products).


With a formal training as a process engineer /process systems engineer and a specialization in process modeling, you will have demonstrated skills in the field of mechanistic, hybrid and/or data-driven modelling methodologies to support process design, optimization, and process control activities for upstream biopharmaceutical processes.


  • As part of matrix project teams, develop and deploy mechanistic, hybrid and data-driven modeling solutions to support upstream process development activities for a broad range of biopharmaceuticals.

  • Use programming languages such as Python, MATLAB, R to translate complex mathematical models into clean and reusable codes for model use and implementation.

  • In coordination with the process development group and working closely with the Data Science team, design and analyze targeted experiments required to calibrate and verify model performance.

  • Act as a change agent to support the implementation of process modeling in established cell culture process development workflows.

  • Document progress against deliverables with rigorous scientific communication via technical presentations, reports and, when appropriate, scientific publications.

  • Maintain a communication plan with key stakeholders and partners across departments.

  • For this position, domain knowledge in cell culture process development and manufacturing (i.e. fed-batch and perfusion bioreactors, harvest operations) is required.

  • This is an exciting opportunity to demonstrate the benefits of process modelling and data science in a cutting-edge scientific department developing the next generation of Sanofi medicines that will improve the quality of life for patients across the world.


About you

  • Process systems engineer/modeler with a PhD in Chemical or Biochemical Engineering and a minimum of 2 years of industrial experience (or MSc with 7 years of industrial experience)

  • Domain knowledge in cell culture process development with demonstrated industrial applications or academic publications in this field.

  • Proven track record of developing and deploying cell culture process models (mechanistic, hybrid or data-driven) in an industrial environment to support CMC process development activities.

  • Demonstrated ability to translate mathematical models into computer programs using programming languages such as MATLAB, R, Python or similar.

  • Excellent communication skills in an international environment.

  • Prior experience with cell metabolism modelling (either mechanistic or data-driven), metabolic network analysis, and media development.

  • Prior experience with both mammalian and microbial processes.

  • Prior experience with hybrid modelling methodologies for cell culture process development.

  • Demonstrated knowledge and application of chemometrics and machine learning methodologies to support cell culture process development and tech transfer activities (e.g. dynamic PCA /golden batch trajectory modelling).

  • Knowledge/ experience with process simulation software (e.g. gPROMS) and integrated systems modelling applications (i.e. flowsheet modelling).

  • Solid track record of publications in the field of process modelling/process simulation for upstream biopharmaceutical processes in peer reviewed journals.

  • Beyond technical skills you will also have a solid track record in project management with an ability to communicate with transparency with your peers and with senior stakeholders.


Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.


Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.




*Pursue progress , discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people -- people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.


At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.


Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

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